Sulfachloropyrazine sodium

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

磺胺氯吡嗪钠是一种抗原虫药，具有抗菌和抗球虫作用。

Sulfachloropyrazine sodium is an antiprotozoalwith antibacterial and anticoccidial effects.

The elimination of Sulfaclozine in the three systems: UV/TiO2, UV/K2S2O8, and UV/TiO2/K2S2O8. Sulfaclozine is weakly adsorbed on the surface of TiO2 at pH 7 (< 5%) but efficiently eliminated with the following three systems: UV/TiO2, UV/K2S2O8, and UV/TiO2/K2S2O8 in ultra pure water. Moreover, 12 of Sulfaclozine by-products are identified and reaction pathways show that, in addition of ?OH and SO4?? radicals, the conduction-band electrons are responsible for the formation of some main by-products either directly or by the formation of superoxide radicals.

Sulfaclozine (60 mg/kg; intravenous injection or oral administration; male broiler chickens) can be used primarily for the treatment of parasitic and microbial infections of the digestive tract rather than for the treatment of systemic infections. Animal Model:14 male broiler chickens (30-day-old) Dosage:60 mg/kgAdministration:Intravenous injection or oral administration (Pharmacokinetic Analysis)Result:Serum drug concentrations at 0.083, 0.50, 2, 6, 24 and 72h were determined to be 99.62, 83.50, 72.68, 58.43, 38.66 and 13.14 μg/mL, respectively, by intravenous injection. By oral administration were determined as 4.33, 7.95, 16.46, 22.88, 16.03 and 5.74 μg/mL, respectively.

Sulfachloropyrazine | Sulfaclozine

GPCR/G Protein

Antibacterial

bacterial|Parasite

——

——

102-65-8

284.72

C10H9ClN4O2S

>98% (HPLC)

DMSO:29 mg/mL (101.85 mM)

Nc1ccc(cc1)S(=O)(=O)Nc1cncc(Cl)n1

4-Amino-N-(6-chloropyrazin-2-yl)benzenesulfonamide

(-20℃)

With Ice Pack

≥ 2 years